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Potential role of indolelactate and butyrate in multiple sclerosis revealed by integrated microbiome-metabolome analysis

1 Apr 2021

Abstract excerpt

Multiple sclerosis (MS) is an immune-mediated disease whose precise etiology is unknown. Several studies found alterations in the microbiome of individuals with MS, but the mechanism by which it may affect MS is poorly understood. Here we analyze the microbiome of 129 individuals with MS and find that they harbor distinct microbial patterns compared with controls. To study the functional consequences of these...

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PMID: 33948576
DOI: 10.1016/j.xcrm.2021.100246

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