Article

Protein covariance networks reveal interactions important to the emergence of SARS coronaviruses as human pathogens

2020-06-06

Abstract excerpt

SARS-CoV-2 is one of three recognized coronaviruses (CoVs) that have caused epidemics or pandemics in the 21 st century and that have likely emerged from animal reservoirs based on genomic similarities to bat and other animal viruses. Here we report the analysis of conserved interactions between amino acid residues in proteins encoded by SARS-CoV-related viruses. We identified pairs and networks of residue varian...

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Literature Corpus work: d3dd01d1-0732-5991-bf3c-5c1617e62214
DOI: 10.1101/2020.06.05.136887

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