Article
Elucidation of the phenotypic, functional, and molecular topography of a myeloerythroid progenitor cell hierarchy.
Cell stem cell - 11 Oct 2007
Pronk Cornelis J H, Rossi Derrick J, Månsson Robert, Attema Joanne L, Norddahl Gudmundur Logi, Chan Charles Kwok Fai, Sigvardsson Mikael, Weissman Irving L, Bryder David
Abstract excerpt
The major myeloid blood cell lineages are generated from hematopoietic stem cells by differentiation through a series of increasingly committed progenitor cells. Precise characterization of intermediate progenitors is important for understanding fundamental differentiation processes and a variety of disease states, including leukemia. Here, we evaluated the functional in vitro and in vivo potentials of a range of...
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