Article

A mechanism-aware stoichiometry platform resolves functional viral thresholds and induces antiviral hypersensitivity

2026-02-10

Abstract excerpt

Antiviral discovery is frequently hindered by a ‘stoichiometric blind spot’—a lack of resolution regarding the functional density of viral enzymes required for replication. Traditional screening pipelines rely on target-based or phenotypic assays that cannot distinguish between simple molecular binding and the crossing of a functional ‘stoichiometric cliff.’ Here, we present a mechanism-aware platform that resolve...

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Literature Corpus work: d3ad4267-eb4f-5d33-947c-641b1d6484a0
DOI: 10.64898/2026.02.09.704886

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