Article

The transcription factor RIP140 regulates interferon γ signaling in breast cancer

2024-02-20

Abstract excerpt

<h4>ABSTRACT</h4> RIP140 (receptor interacting protein of 140 kDa) is an important player in breast cancer (BC) by regulating key cellular pathways such as nuclear hormone receptors signaling. In order to identify additional genes specifically regulated by RIP140 in BC, we performed an RNA sequencing after silencing its expression in MCF-7 cells. We identified the interferon γ (IFNγ) signaling as being substantia...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: d3a41521-607c-530a-ab67-f4a3a5894089
DOI: 10.1101/2024.02.15.580503

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

The transcription factor RIP140 regulates interferon γ signaling in breast cancerDOI 10.1101/2024.02.15.580503Read

The Transcriptional Coregulator RIP140 Represses E2F1 Activity and Discriminates Breast Cancer SubtypesSemantic proximity Read

A Human Genome-Wide RNAi Screen Reveals Diverse Modulators that Mediate IRE1α–XBP1 ActivationSemantic proximity Read

Candidate tumor suppressor gene IRF6 is involved in human breast cancer pathogenesis via modulating PI3K-regulatory subunit PIK3R2 expressionSemantic proximity Read

RIP140 inhibits glycolysis-dependent proliferation of breast cancer cells by regulating GLUT3 expression through transcriptional crosstalk between hypoxia induced factor and p53Semantic proximity Read

Transcriptional coregulator RIP140: an essential regulator of physiologySemantic proximity Read

<i>Bromodomain 4</i> activation predicts breast cancer survivalSemantic proximity Read

High-throughput assay confirmation of a T-cell receptor pre-mRNA fragment as a blood-based inflammatory breast cancer biomarkerSemantic proximity Read

Coactivator function of RIP140 for NFκB/RelA-dependent cytokine gene expressionSemantic proximity Read

MicroRNA-138-5p inhibits cell migration, invasion and EMT in breast cancer by directly targeting RHBDD1Semantic proximity Read

The UPR Transducer IRE1 Promotes Breast Cancer Malignancy by Degrading Tumor Suppressor microRNAsSemantic proximity Read

KDELR2 promotes breast cancer proliferation via HDAC3‐mediated cell cycle progressionSemantic proximity Read

Methylation-Mediated Silencing of RBP7 Promotes Breast Cancer Progression Through PPAR and PI3K/AKT PathwaySemantic proximity Read