Article

High-throughput assay confirmation of a T-cell receptor pre-mRNA fragment as a blood-based inflammatory breast cancer biomarker

2025-08-21

Abstract excerpt

Previous TGIRT-seq analysis of RNAs in Inflammatory Breast Cancer (IBC) patient tumors, peripheral blood mononuclear cells (PBMCs) and plasma identified a short T-cell receptor mRNA fragment ( TRBJ1-6 ) as a potential IBC biomarker that was detected in plasma samples from IBC patients but not patients with non-inflammatory breast cancer or healthy donors. Here, we traced the origin of this TRBJ1-6 RNA fragment to...

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Literature Corpus work: bf483d36-a7e0-5531-b727-efb7a9093ac0
DOI: 10.1101/2025.08.19.25333925

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