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Article

KDELR2 promotes breast cancer proliferation via HDAC3‐mediated cell cycle progression

19 Jun 2021

Abstract excerpt

BACKGROUND: Histone deacetylases (HDACs) engage in the regulation of various cellular processes by controlling global gene expression. The dysregulation of HDACs leads to carcinogenesis, making HDACs ideal targets for cancer therapy. However, the use of HDAC inhibitors (HDACi) as single agents has been shown to have limited success in treating solid tumors in clinical studies. This study aimed to identify a novel...

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PMID: 34146461
DOI: 10.1002/cac2.12180

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