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Article

High multiplex, digital spatial profiling of proteins and RNA in fixed tissue using genomic detection methods

2019-02-22

Abstract excerpt

<h4>ABSTRACT</h4> We have developed Digital Spatial Profiling (DSP), a non-destructive method for high-plex spatial profiling of proteins and RNA, using oligonucleotide detection technologies with unlimited multiplexing capability. The key breakthroughs underlying DSP are threefold: (1) multiplexed readout of proteins/RNA using oligo-tags; (2) oligo-tags attached to affinity reagents (antibodies/RNA probes) throu...

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Literature Corpus work
d380ae99-6a2f-5e8d-a902-45f19470d72e
DOI
10.1101/559021
Open publication

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High multiplex, digital spatial profiling of proteins and RNA in fixed tissue using genomic detection methodsDOI 10.1101/559021
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