Article

ZBTB24 is a conserved multifaceted transcription factor at genes and centromeres that governs the DNA methylation state and expression of satellite repeats

2023-09-01

Abstract excerpt

<h4>ABSTRACT</h4> Since its discovery as an Immunodeficiency with Centromeric instability and Facial anomalies syndrome-causative gene, ZBTB24 has emerged as a key player in DNA methylation, immunity and development. By extensively analyzing ZBTB24 genomic functions in ICF-relevant mouse and human cellular models, we revealed here its multiple facets as a transcription factor, with key roles in immune response-re...

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Literature Corpus work: d367f91b-0faa-512c-b601-8a80b12769c8
DOI: 10.1101/2023.08.31.555516

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