Article

Protective Effect of Placental Mesenchymal Stromal Cells in an In Vitro Model of Parkinson’s Disease Using Differentiated Neuroblastoma Cells

2026-03-31

Abstract excerpt

Parkinson’s disease (PD) is the second most prevalent neurodegenerative disorder, characterized by the accumulation of misfolded α-synuclein (α-syn), with the progressive loss of dopaminergic neurons in the substantia nigra. Given the limitations of current therapies, mesenchymal stromal cell (MSC) transplantation has emerged as a promising neuroprotective strategy. This study evaluated the in vitro neuroprotectiv...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: d3665a13-5369-5ac6-824e-5e3bf65c8634
DOI: 10.20944/preprints202603.2483.v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Protective Effect of Placental Mesenchymal Stromal Cells in an In Vitro Model of Parkinson’s Disease Using Differentiated Neuroblastoma CellsDOI 10.20944/preprints202603.2483.v1Read

Bone marrow stromal cells as replacement cells for Parkinson's disease: generation of an anatomical but not functional neuronal phenotype.Semantic proximity Read

Stem cell-based therapy for Parkinson's disease with a focus on human endometrium-derived mesenchymal stem cells.Semantic proximity Read

Parkinson's Disease and Mesenchymal Stem Cells: Potential for Cell-Based TherapySemantic proximity Read

Dopaminergic neurons from midbrain-specified human embryonic stem cell-derived neural stem cells engrafted in a monkey model of Parkinson's disease.Semantic proximity Read

Therapy With Mesenchymal Stem Cells in Parkinson DiseaseSemantic proximity Read

22-hydroxycholesterol leads to efficient dopaminergic specification of human Mesenchymal Stem CellsSemantic proximity Read

In vitro assays for neural stem cell differentiation: induction of dopaminergic phenotype.Semantic proximity Read

PARKIN overexpression in human mesenchymal stromal cells from Wharton's jelly suppresses 6-hydroxydopamine-induced apoptosis: Potential therapeutic strategy in Parkinson's disease.Semantic proximity Read

Autologous Versus Allogeneic iPSC-Derived Dopaminergic Neuron Therapy for Parkinson’s Disease: Molecular Mechanisms and Translational Trade-OffsSemantic proximity Read

Synergetic Therapeutic Efficacy of Fasudil and Bone Marrow Derived-Neuronal Stem Cell in a Parkinson's Disease Mouse ModelSemantic proximity Read

Cell Therapy in Parkinson’s DiseaseSemantic proximity Read

Therapeutic effects of umbilical cord MSC-derived induced neuronal cells in a rat Parkinson's modelSemantic proximity Read