Article

Massively parallel pooled screening reveals genomic determinants of nanoparticle-cell interactions

2021-04-06

Abstract excerpt

To accelerate the translation of cancer nanomedicine, we hypothesize that integrated genomic screens will improve understanding of the cellular processes governing nanoparticle trafficking. We developed a massively parallel high-throughput screening method leveraging barcoded, pooled cancer cell lines annotated with multi-omic data to investigate cell association patterns across a nanoparticle library spanning a r...

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Literature Corpus work: d340b06a-4b1b-518a-b5ed-4fcf6de79f01
DOI: 10.1101/2021.04.05.438521

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