Article

Local PCA Shows How the Effect of Population Structure Differs Along the Genome

2016-08-21

Abstract excerpt

Population structure leads to systematic patterns in measures of mean relatedness between individuals in large genomic datasets, which are often discovered and visualized using dimension reduction techniques such as principal component analysis (PCA). Mean relatedness is an average of the relationships across locus-specific genealogical trees, which can be strongly affected on intermediate genomic scales by linked...

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Literature Corpus work: d33d9c6d-a24a-5ece-9376-cd57397a69bd
DOI: 10.1101/070615

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