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Expansion of Artemisinin Partial Resistance Mutations and Lack of Histidine Rich Protein-2 and -3 Deletions in<i>Plasmodium falciparum infections</i>from Rukara, Rwanda

2023-12-18

Abstract excerpt

<h4>Background</h4> Emerging artemisinin resistance and diagnostic resistance are a threat to malaria control in Africa. Plasmodium falciparum kelch13 (K13) propeller-domain mutations that confer artemisinin partial resistance have emerged in Africa. K13-561H was initially described at a frequency of 7.4% from Masaka in 2014-2015 but not present in nearby Rukara. By 2018, 19.6% of isolates in Masaka and 22% of iso...

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Literature Corpus work
d2cdab32-6ba7-5ef6-b412-877fcf904190
DOI
10.1101/2023.12.17.23300081
Open publication

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Expansion of Artemisinin Partial Resistance Mutations and Lack of Histidine Rich Protein-2 and -3 Deletions in<i>Plasmodium falciparum infections</i>from Rukara, RwandaDOI 10.1101/2023.12.17.23300081
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