Prevalence of mutations associated with artemisinin partial resistance and sulfadoxine-pyrimethamine resistance in 13 regions in Tanzania in 2021: a cross-sectional survey.

doi:10.1016/S2666-5247(24)00160-5

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Article

Prevalence of mutations associated with artemisinin partial resistance and sulfadoxine-pyrimethamine resistance in 13 regions in Tanzania in 2021: a cross-sectional survey.

The Lancet. Microbe - 1 Oct 2024

Juliano Jonathan J, Giesbrecht David J, Simkin Alfred, Fola Abebe A, Lyimo Beatus M, Pereus Dativa, Bakari Catherine, Madebe Rashid A, Seth Misago D, Mandara Celine I, Popkin-Hall Zachary R, Moshi Ramadhan, Mbwambo Ruth B, Niaré Karamoko, MacInnis Bronwyn, Francis Filbert, Mbwambo Daniel, Garimo Issa, Chacky Frank, Aaron Sijenunu, Lusasi Abdallah, Molteni Fabrizio, Njau Ritha J A, Nhiga Samwel L, Mohamed Ally, Bailey Jeffrey A, Ishengoma Deus S

Abstract excerpt

BACKGROUND: The emergence of the artemisinin partial resistance (ART-R) mutation in the Plasmodium falciparum kelch13 gene (k13), Arg561His, in Rwanda and the regional presence of polymorphisms affecting sulfadoxine-pyrimethamine have raised concern in neighbouring Tanzania. The goal of this study was to assess the status of antimalarial resistance in Tanzania, with a focus on the border with Rwanda, to...

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PMID: 39159629
DOI: 10.1016/S2666-5247(24)00160-5
PMCID: PMC11464622

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