Article

Deep generative modeling of sample-level heterogeneity in single-cell genomics

2022-10-06

Abstract excerpt

The field of single-cell genomics is now observing a marked increase in the prevalence of cohort-level studies that include hundreds of samples and feature complex designs. These data have tremendous potential for discovering how sample or tissue-level phenotypes relate to cellular and molecular composition. However, current analyses are based on simplified representations of these data by averaging information ac...

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Literature Corpus work: d2bcab21-28b7-5df1-914c-4f8c22295b9d
DOI: 10.1101/2022.10.04.510898

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