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scSemiProfiler: Advancing Large-scale Single-cell Studies through Semi-profiling with Deep Generative Models and Active Learning

2023-11-21

Abstract excerpt

<h4> Abstract </h4> Single-cell sequencing is a crucial tool for dissecting the cellular intricacies of complex diseases. Its prohibitive cost, however, hampers its application in expansive biomedical studies. Traditional cellular deconvolution approaches can infer cell type proportions from more affordable bulk sequencing data, yet they fall short in providing the detailed resolution required for single-cell-le...

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Literature Corpus work
22a176a6-5918-5d84-95e5-a638985674e4
DOI
10.1101/2023.11.20.567929
Open publication

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