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Unagi: Deep Generative Model for Deciphering Cellular Dynamics and In-Silico Drug Discovery in Complex Diseases

2023-12-18

Abstract excerpt

<title>Abstract</title> <p>Human diseases are characterized by intricate cellular dynamics. Single-cell sequencing provides critical insights, yet a persistent gap remains in computational tools for detailed disease progression analysis and targeted in-silico drug interventions. We introduce UNAGI, a deep generative neural network tailored to analyze time-series single-cell transcriptomic data. This innovative to...

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Literature Corpus work
e3b72cac-ffa9-5b57-8263-c6d95bd87309
DOI
10.21203/rs.3.rs-3676579/v1
Open publication

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