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Article

Chondrocyte Aging: The Molecular Determinants and Therapeutic Opportunities

14 Jul 2021

Abstract excerpt

Osteoarthritis (OA) is a joint degenerative disease that is an exceedingly common problem associated with aging. Aging is the principal risk factor for OA, but damage-related physiopathology of articular chondrocytes probably drives the mechanisms of joint degeneration by a progressive decline in the homeostatic and regenerative capacity of cells. Cellular aging is the manifestation of a complex interplay of...

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PMID: 34336816
DOI: 10.3389/fcell.2021.625497

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