Article

Using TCR and BCR sequencing to unravel the role of T and B cells in abdominal aortic aneurysm

2022-12-03

Abstract excerpt

<h4>Background</h4> Abdominal aortic aneurysm (AAA) is a life-threatening cardiovascular disease, and the pathogenesis is still poorly understood. Recent evidence suggests that AAA displays characteristics of an autoimmune disease and it gained increasing prominence that specific antigen-driven T cells in the aortic tissue may contribute to the initial immune response. Single-cell RNA T- and B cell receptor (TCR...

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Literature Corpus work: d291fc02-6ab8-5537-93e1-24b0845c4e11
DOI: 10.1101/2022.12.01.518788

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