Article

Spatiotemporal dynamics of alphaherpesviral latency and reactivation in the murine central nervous system

2025-09-16

Abstract excerpt

Alphaherpesviruses, including Herpes Simplex Virus 1 (HSV-1) and Pseudorabies Virus (PrV), establish lifelong latency in the nervous system and can cause recurrent disease. While latency has classically been attributed to peripheral sensory ganglia, accumulating evidence indicates that the central nervous system (CNS) also act as a relevant reservoir for viral latency and reactivation. Here, we investigated the CN...

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Identifiers and source

Literature Corpus work: d27105b0-d987-5f7f-b79e-fc6b70f9718f
DOI: 10.1101/2025.09.11.675502

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