Article

Deciphering 3’ UTR mediated gene regulation using interpretable deep representation learning

2023-09-12

Abstract excerpt

The 3’untranslated regions (3’UTRs) of messenger RNAs contain many important cis-regulatory elements that are under functional and evolutionary constraints. We hypothesize that these constraints are similar to grammars and syntaxes in human languages and can be modeled by advanced natural language models such as Transformers, which has been very effective in modeling protein sequence and structures. Here we descri...

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Literature Corpus work: d6deaac4-980f-5612-9762-198b6d03ce0a
DOI: 10.1101/2023.09.08.556883

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