Article

Comprehensive methylome-wide association study with methylation-based WGCNA profiling and functional enrichment analyses in drug-induced liver injury

2026-06-11

Abstract excerpt

<title>Abstract</title> <p> Background Idiosyncratic drug-induced liver injury (DILI) is a rare, unpredictable and host-specific immune-mediated adverse reaction to drugs, herbal and dietary supplements. DILI is a complex disease whose presentation is influenced by multiple host and environmental factors. The latter modulate gene expression through epigenetic regulatory mechanisms, such as DNA methylation. This...

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Literature Corpus work: d1fdf71b-bc02-5412-86ea-5fe76d78c48e
DOI: 10.21203/rs.3.rs-9038512/v1

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