The XenCart Protocol: A Method for Alcian Blue Labeling and Quantitative Analysis of Craniofacial Cartilage in <i>Xenopus</i>

Abstract excerpt

Craniofacial birth defects, such as cleft lip and palate, are among the most common congenital anomalies and often arise from disruptions in early facial patterning. Many of these defects are linked to environmental teratogens, yet such exposures cannot be directly tested in humans, making animal models essential for evaluating developmental risks. Xenopus laevis offers a powerful solution: its tadpoles develop e...

Topics

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• Craniofacial Abnormalities
• Disease Models, Animal
• Gene Expression Regulation, Developmental
• Genetic Predisposition to Disease
• Models, Genetic
• Mutation
• Prenatal Substance Exposure Effects
• Signal Transduction

Identifiers and source

Literature Corpus work

d19e648a-13d8-5d9e-b489-b03bfcd963f6

DOI

10.64898/2026.05.30.728963