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Near-Native Visualization of SARS-CoV-2 Induced Membrane Remodeling and Virion Morphogenesis

14 Dec 2022

Abstract excerpt

Infection with the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the causative agent of the COVID-19 pandemic, leads to profound remodeling of cellular membranes, promoting viral replication and virion assembly. A full understanding of this drastic remodeling and the process of virion morphogenesis remains lacking. In this study, we applied room temperature transmission electron microscopy (TEM)...

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PMID: 36560790
DOI: 10.3390/v14122786

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