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Long-read RNA sequencing identifies polyadenylation elongation and differential transcript usage of host transcripts during SARS-CoV-2 <i>in vitro</i> infection

2021-12-15

Abstract excerpt

Better methods to interrogate host-pathogen interactions during Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infections are imperative to help understand and prevent this disease. Here we implemented RNA-sequencing (RNA-seq) combined with the Oxford Nanopore Technologies (ONT) long-reads to measure differential host gene expression, transcript polyadenylation and isoform usage within various epithe...

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Identifiers and source

Literature Corpus work
d183790e-f548-5db5-acfc-8b876909ede8
DOI
10.1101/2021.12.14.472725
Open publication

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Long-read RNA sequencing identifies polyadenylation elongation and differential transcript usage of host transcripts during SARS-CoV-2 <i>in vitro</i> infectionDOI 10.1101/2021.12.14.472725
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