Article

Recurrent loss of an immunity gene that protects <i>Drosophila</i> against a major natural parasite

2022-05-28

Abstract excerpt

Polymorphisms in immunity genes can have large effects on susceptibility to infection. To understand the origins of this variation, we investigated the genetic basis of resistance to the parasitoid wasp Leptopilina boulardi in Drosophila melanogaster . A cis -regulatory polymorphism in the gene Lectin-24A abolishes expression after infection, strongly reducing survival. Other null mutations have arisen repeate...

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Literature Corpus work: d14c1a51-17e7-5ad3-b06f-6d1cc00d01e1
DOI: 10.1101/2022.05.27.493757

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