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Article

Constitutive activation of cellular immunity underlies the evolution of resistance to infection in Drosophila

24 Dec 2020

Abstract excerpt

Organisms rely on inducible and constitutive immune defences to combat infection. Constitutive immunity enables a rapid response to infection but may carry a cost for uninfected individuals, leading to the prediction that it will be favoured when infection rates are high. When we exposed populations of Drosophila melanogaster to intense parasitism by the parasitoid wasp Leptopilina boulardi, they evolved...

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PMID: 33357377
DOI: 10.7554/elife.59095

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