Article

A Functional Reference Map of RNF8 Interactome in Cancers

2022-03-29

Abstract excerpt

<h4>Background: </h4> RNF8 was an E3 ligase identiﬁed as a critical DNA damage-responsive protein. Recently, massive reports showed that RNF8 could be used as an important therapeutic target for cancer chemo/radiotherapy. However, the in-depth understanding of RNF8 remains limited for the lack of its interactome reference map and comprehensive analysis in divergent cancers, which underscore the need to identify th...

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Literature Corpus work: 5ca31acc-d2ea-5d73-b1ce-7757c6f4b0d2
DOI: 10.21203/rs.3.rs-1450803/v1

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