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Article

Identification of a genetic region linked to tolerance to MRSA infection using Collaborative Cross mice.

PLoS genetics - 1 Aug 2024

Nagarajan Aravindh, Scoggin Kristin, Adams L Garry, Threadgill David, Andrews-Polymenis Helene

Abstract excerpt

Staphylococcus aureus (S. aureus) colonizes humans asymptomatically but can also cause opportunistic infections, ranging from mild skin infections to severe life-threatening conditions. Resistance and tolerance are two ways a host can survive an infection. Resistance is limiting the pathogen burden, while tolerance is limiting the health impact of a given pathogen burden. In previous work, we established that...

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PMID: 39178306
DOI: 10.1371/journal.pgen.1011378
PMCID: PMC11407622

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