Article

The effect of surfactant phospholipids on mucus hypersecretion in stimulated lung epithelial cells

2005-01-01

Abstract excerpt

Mucin hypersecretion in the airways is a hallmark of Chronic Obstructive Pulmonary Diseases (COPD) and in particular of chronic bronchitis. This study investigates how bacterial products such as LPS affect mucin production (the main constituent of mucus) and how surfactant phospholipids may modulate this effect. In two human bronchoepithelial cell lines, NCI-H292 and Calu-3, both of which express mucin gene and se...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: d09aa666-e28f-55c7-b892-6f13a26c9156
DOI: 10.25401/cardiffmet.20332221.v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

The effect of surfactant phospholipids on mucus hypersecretion in stimulated lung epithelial cellsDOI 10.25401/cardiffmet.20332221.v1Read

Airway mucosa: secretory cells, mucus and mucin genesSemantic proximity Read

Polarized cytokine release from airway epithelium differentially influences macrophage phenotype.Semantic proximity Read

Airway mucus hypersecretion in asthma: an undervalued pathology?Semantic proximity Read

Mucus and MUC in asthma.Semantic proximity Read

<i>Mycoplasma pneumoniae</i>induces airway epithelial cell expression of MUC5AC in asthmaSemantic proximity Read

Model Systems for Investigating Mucin Gene Expression in Airway DiseasesSemantic proximity Read

The novel surfactant protein SP-H enhances the phagocytosis efficiency of macrophage-like cell lines U937 and MH-SSemantic proximity Read

Proteomics as the Tool to Search for Lung Disease Markers in Bronchoalveolar LavageSemantic proximity Read

MUC5B regulates goblet cell differentiation and reduces inflammation in a murine COPD modelSemantic proximity Read

CD44 Regulates Macrophage Recruitment to the Lung in Lipopolysaccharide-Induced Airway DiseaseSemantic proximity Read

Mucin Gene Expression during Differentiation of Human Airway Epithelia <i>In Vitro</i> : MUC4 and MUC5B Are Strongly InducedSemantic proximity Read

Anti-infective control in human bronchiolar epithelial cells by mucin phenotypic changes following uptake of N-acetyl-L-cysteine.Semantic proximity Read