Article

Refeeding-associated AMPK <sub>γ1</sub> complex activity is a hallmark of health and longevity

2022-12-08

Abstract excerpt

Late-life-initiated dietary interventions negligibly extend longevity or reduce frailty, yet the reason remains unknown. We investigated the age-related changes associated with the fasting response in adipose tissue of the short-lived killifish N. furzeri . Transcriptomic analysis revealed the presence of a fasting-like transcriptional program (FLTP) in old animals that is irrespective of their nutritional status...

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Identifiers and source

Literature Corpus work: d099404e-f16a-5a2d-9b36-016226b583ac
DOI: 10.1101/2022.12.05.519139

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