Article
Trafficking through COPII stabilises cell polarity and drives secretion during Drosophila epidermal differentiation.
PloS one - 24 May 2010
Norum Michaela, Tång Erika, Chavoshi Tina, Schwarz Heinz, Linke Dirk, Uv Anne, Moussian Bernard
Abstract excerpt
BACKGROUND: The differentiation of an extracellular matrix (ECM) at the apical side of epithelial cells implies massive polarised secretion and membrane trafficking. An epithelial cell is hence engaged in coordinating secretion and cell polarity for a correct and efficient ECM formation. PRINCIPAL FINDINGS: We are studying the molecular mechanisms that Drosophila tracheal and epidermal cells deploy to form their...
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