Article

Schwann cell-specific ablation of Beclin 1 impairs peripheral myelination and leads to a progressive motor and sensory neuropathy

2023-11-16

Abstract excerpt

<title>Abstract</title> <p>The core component of the class III phosphatidylinositol 3-kinase complex, Beclin 1, takes part in different protein networks, thus switching its role from inducing autophagy to regulating autophagosomal maturation and endosomal trafficking. While assessed in neurons, astrocytes and microglia, its role was far less investigated in myelinating glia, including Schwann cells (SCs), respons...

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Literature Corpus work: d06b6fc5-8b50-52b3-9a18-3f6ac097542c
DOI: 10.21203/rs.3.rs-3596800/v1

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Schwann cell-specific ablation of Beclin 1 impairs peripheral myelination and leads to a progressive motor and sensory neuropathyDOI 10.21203/rs.3.rs-3596800/v1Read

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