Article

<i>In silico</i> analysis of miR-137 transcription inhibition in homozygous (T/T) schizophrenic patients: a pilot study.

2019-03-01

Abstract excerpt

MicroRNA miR-137 single nucleotide polymorphism (rs1625579 SNP) is strongly associated with the worsening of schizophrenia symptoms and is involved in miR-137 gene suppression. MicroRNA miR-137 regulates synaptogenesis, neural plasticity and suppresses a variety of cancertypes. Based on in silico predictions of the current MIR137 Host Gene with and without the SNP, it can be hypothesized that the mutation reversi...

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Literature Corpus work: d042240a-f84a-5a35-a697-bcc93794ecd0
DOI: 10.7287/peerj.preprints.27560v1

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