Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A long noncoding RNA promotes parasite differentiation in African trypanosomes

15 Jun 2022

Abstract excerpt

The parasite Trypanosoma brucei causes African sleeping sickness that is fatal to patients if untreated. Parasite differentiation from a replicative slender form into a quiescent stumpy form promotes host survival and parasite transmission. Long noncoding RNAs (lncRNAs) are known to regulate cell differentiation in other eukaryotes. To determine whether lncRNAs are also involved in parasite differentiation, we...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related molecular mechanisms research
Share to RNA modifications and cancer
Share to Trypanosoma species research and implications

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35704590
DOI: 10.1126/sciadv.abn2706

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A long noncoding RNA promotes parasite differentiation in African trypanosomesPMID 35704590Read ↗

A long non-coding RNA controls parasite differentiation in African trypanosomesSemantic proximity Read ↗

Single cell transcriptomic analysis of bloodstream form <i>Trypanosoma brucei</i> reconstructs cell cycle progression and differentiation via quorum sensingSemantic proximity Read ↗

Assembling the components of the quorum sensing pathway in A frican trypanosomesSemantic proximity Read ↗

The <i>Trypanosoma cruzi</i> cell atlas; a single-cell resource for understanding parasite population heterogeneity and differentiationSemantic proximity Read ↗

Single-cell transcriptomic analysis of bloodstream Trypanosoma brucei reconstructs cell cycle progression and developmental quorum sensing.Semantic proximity Read ↗

RNA-Seq analysis validates the use of culture-derived Trypanosoma brucei and provides new markers for mammalian and insect life-cycle stagesSemantic proximity Read ↗

Extensive Translational Regulation through the Proliferative Transition of Trypanosoma cruzi Revealed by Multi-OmicsSemantic proximity Read ↗

A bioinformatic approach for the prediction and functional classification of <i>Toxoplasma gondii</i> long non-coding RNAsSemantic proximity Read ↗

Transcriptomic analysis of N-terminal mutated <i>Trypanosoma cruzi</i> UBP1 knockdown underlines the importance of this RNA-binding protein in parasite developmentSemantic proximity Read ↗

Identification of positive and negative regulators in the stepwise developmental progression towards infectivity in Trypanosoma bruceiSemantic proximity Read ↗

Transcriptomic analysis of N-terminal mutated Trypanosoma cruzi UBP1 knockdown underlines the importance of this RNA-binding protein in parasite development.Semantic proximity Read ↗

Unexpected plasticity in the life cycle of Trypanosoma bruceiSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.