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Assembling the components of the quorum sensing pathway in A frican trypanosomes

29 Jan 2015

Abstract excerpt

African trypanosomes, parasites that cause human sleeping sickness, undergo a density-dependent differentiation in the bloodstream of their mammalian hosts. This process is driven by a released parasite-derived factor that causes parasites to accumulate in G1 and become quiescent. This is accompanied by morphological transformation to 'stumpy' forms that are adapted to survival and further development when taken...

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PMID: 25630552
DOI: 10.1111/mmi.12949

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