Back to search

Article

A neuroprotective role of Ufmylation through Atg9 in the aging brain of Drosophila

2022-06-07

Abstract excerpt

<title>Abstract</title> <p>Ufmylation is a recently identified small ubiquitin-like modification, whose biological function and relevant cellular targets are poorly understood. Here we present evidence of a neuroprotective role for Ufmylation involving Autophagy-related gene 9 (Atg9) in the aging brain of <italic>Drosophila</italic>. The Ufm1 system ensures the health of aged neurons via Atg9 by coordinating auto...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
cfc84fbd-6a4b-5d1f-b51b-7031811e7aa9
DOI
10.21203/rs.3.rs-1678775/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
A neuroprotective role of Ufmylation through Atg9 in the aging brain of DrosophilaDOI 10.21203/rs.3.rs-1678775/v1
A neuroprotective role of Ufmylation through Atg9 in the aging brain of DrosophilaSemantic proximity
Drosophila Gyf/GRB10 interacting GYF protein is an autophagy regulator that controls neuron and muscle homeostasis.Semantic proximity
The many connections of UFMylation with Alzheimer’s disease: a comprehensive reviewSemantic proximity
Promoting basal levels of autophagy in the nervous system enhances longevity and oxidant resistance in adult DrosophilaSemantic proximity
On the Fly: Recent Progress on Autophagy and Aging in DrosophilaSemantic proximity
The Post-Translational Role of UFMylation in Physiology and DiseaseSemantic proximity
Deficiency of murine UFM1-specific E3 ligase causes microcephaly and inflammationSemantic proximity
SQSTM1/p62 UFMylation Enhances Autophagic Clearance of Pathogenic Mutant Huntingtin.Semantic proximity
C16ORF70/MYTHO promotes healthy aging in C.elegans and prevents cellular senescence in mammalsSemantic proximity
The emerging roles of UFMylation in the modulation of immune responsesSemantic proximity
Systematic Analysis of UFMylation Family Genes in Tissues of Mice with Metabolic Dysfunction-Associated Steatotic Liver DiseaseSemantic proximity
The autophagy-related gene Atg101 in Drosophila regulates both neuron and midgut homeostasisSemantic proximity
Select a neighboring publication to make it the new centre.