Article

A tumor suppressor role of the miR-15b/16-2 cluster in T-cell acute lymphoblastic leukemia

2025-07-10

Abstract excerpt

<h4>ABSTRACT</h4> T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive hematological malignancy arising from the neoplastic transformation of immature T cells during their development in the thymus. Deciphering the developmental programs whose dysregulation leads to T-ALL pathogenesis is critical for the development of novel targeted therapies, which remain an urgent unmet need for the treatment of this d...

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Literature Corpus work: cfbc9c3d-8924-5059-9f03-174c8fe429bb
DOI: 10.1101/2025.07.07.663472

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