Article

Episodic live imaging of cone photoreceptor maturation in GNAT2-EGFP retinal organoids

2023-03-01

Abstract excerpt

Fluorescent reporter pluripotent stem cell (PSC) derived retinal organoids are powerful tools to investigate cell type-specific development and disease phenotypes. When combined with live imaging, they enable direct and repeated observation of cell behaviors within a developing retinal tissue. Here, we generated a human cone photoreceptor reporter line by CRISPR/Cas9 genome editing of WTC11-mTagRFPT-LMNB1 human in...

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Identifiers and source

Literature Corpus work: cf34f341-a84b-555c-9232-16a64a4efaa4
DOI: 10.1101/2023.02.28.530518

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