Article

miR-135a-5p in Exosomes Promotes Childhood Nephrotic Syndrome via GSK-3β and TGF-β1 Crosstalk

2025-08-26

Abstract excerpt

<title>Abstract</title> <p>Background Nephrotic syndrome (NS) is an autoimmune kidney disorder that is characterized by severe protein loss in urine, which results in edema, hyperlipidemia, and hypoalbuminemia. Glucocorticoid therapy is the main treatment for NS patients; however, the unsuitable treatment of NS can lead to chronic glomerulonephritis and, in turn, end-stage renal disease (ESRD). Genetic and epigen...

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Literature Corpus work: 88379245-cd93-55e4-bf2e-d18a9c89b7e4
DOI: 10.21203/rs.3.rs-7328776/v1

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