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Chronic Kidney Disease–Associated Pruritus is Caused by Dysregulated Ion Channels in Sensory Neurons

2019-09-14

Abstract excerpt

<h4>Background: </h4> We investigated ion channels at the skin, including peripheral nerve endings, which serve as output machines and molecular integrators of many pruritic inputs mainly received by multiple G protein-coupled receptors (GPCRs). <h4>Methods:</h4> Based on the level of chronic kidney disease&ndash;associated pruritus (CKD-aP), subjects were divided into two groups: non-CKD-aP (no or slight pruritus...

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Literature Corpus work
ced58236-a15d-566e-965c-6462e97a3160
DOI
10.20944/preprints201909.0142.v1
Open publication

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