Article

Reference-guided automatic assembly of genomic tandem repeats with only HiFi and Hi-C data enables population-level analysis

2023-12-08

Abstract excerpt

The existing de novo methods of complete genome assembly are not able to generate large-scale pangenomes with complete assemblies due to the shortcomings such as requiring multiple types of sequencing data of high price, requiring large amount of manual curation, and not being able to achieve haplotype-resolved complete assembly of long tandem repeats in most situations. To solve this problem, in this study, we pr...

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Literature Corpus work: ced36ecf-b11d-5a49-a521-5523a9af8fa7
DOI: 10.1101/2023.12.07.570710

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