Article
Ferroptosis and Oral Cancer: Leveraging Iron-Driven Cell Death for Innovative Therapeutic Strategies
2025-01-01
Abstract excerpt
Ferroptosis is a novel form of regulated cell death characterized by iron-dependent lipid peroxidation and distinct morphological changes. This process is driven by key mechanisms, including polyunsaturated fatty acid synthesis, lipid peroxidation, iron metabolism, and the glutathione peroxidase 4 antioxidant system. Owing to their altered redox balance and metabolic states, cancer cells are particularly susceptib...
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Identifiers and source
- Literature Corpus work
- ceb4c478-2c10-5fbc-a4f3-a6a9cfe61455
- DOI
- 10.34133/jbioxresearch.0062