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Ferroptosis and Cancer: Complex Relationship and Potential Application of Exosomes

8 Sept 2021

Abstract excerpt

Cell death induction has become popular as a novel cancer treatment. Ferroptosis, a newly discovered form of cell death, features regulated, iron-dependent accumulation of lipid hydroperoxides. Since this word "ferroptosis" was coined, numerous studies have examined the complex relationship between ferroptosis and cancer. Here, starting from the intrinsic hallmarks of cancer and cell death, we discuss the...

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PMID: 34568341
DOI: 10.3389/fcell.2021.733751

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