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Brahmi Ghrita Exerts Nephroprotective Effects by Restoring Cytoskeletal Integrity and Ion Transport in <i>Drosophila</i> Model of Polycystic Kidney Disease

2026-02-16

Abstract excerpt

<h4>Background</h4> Polycystic kidney disease (PKD) is a genetic disorder characterized by progressive cyst formation, epithelial disorganization, and impaired fluid transport, ultimately leading to renal failure. Disruption of cytoskeletal dynamics and epithelial polarity is central to PKD pathogenesis. Malpighian tubules (MTs) of Drosophila melanogaster serve as a conserved renal analog, and caspase-3/Drice–de...

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Literature Corpus work
ceae387d-c404-53f3-9483-f85eba792e7d
DOI
10.64898/2026.02.13.705756
Open publication

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