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Network pharmacology and an in silico-based study to identify proinflammatory pathways and promising bioactive polyphenols for the treatment of sickle cell anemia

2024-01-30

Abstract excerpt

Sickle cell anemia (SCA) is a disease transmitted as an autosomal recessive Mendelian trait. It causes symptoms that worsen with age, such as acute and chronic pain, chest syndrome, pulmonary hypertension, stroke, kidney disease, and vaso-occlusive crises (VOCs), which are the leading cause of hospitalization and premature death. Although there are existing treatments to manage it, side effects related to VOCs suc...

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Literature Corpus work
ceab4994-2a5b-5ce9-90c3-a3445b51e2b3
DOI
10.21203/rs.3.rs-3894560/v1
Open publication

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