Article

Allelic variations and gene cluster modularity act as non-linear bottlenecks for cholera emergence

2022-09-26

Abstract excerpt

<h4>ABSTRACT</h4> Cholera, an acute secretory diarrhea, is caused by strains from a phylogenetically confined group within the Vibrio cholerae species, the pandemic cholera group (PCG). To date, the molecular and evolutionary factors that enable the isolated emergence of toxigenic V. cholerae from environmental populations remain mostly enigmatic. Comprehensive analyses of over 1,100 V. cholerae genomes, inclu...

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Literature Corpus work: 7dad0964-039a-5875-9c5a-586b7812cc03
DOI: 10.1101/2022.09.26.509565

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