Article

Exploring Perianal Fistulas: Insights into Biochemical, Genetic and Epigenetic Influences – a Comprehensive Review

2025-01-27

Abstract excerpt

The development of perianal fistulas leads to significant decrease in the quality of patients’ lives. The onset of this condition is dependent on many factors, including inflammation or trauma. In the occurrence of Crohn’s Disease-associated fistulas, numerous molecular factors and metabolic pathways are involved. To integrate the current knowledge on the biochemical, genetic, and epigenetic factors taking part in...

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Literature Corpus work: ce354e70-0491-5861-976c-d0a81b0ead5a
DOI: 10.20944/preprints202501.1988.v1

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