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Genetic, Clinical, and Biological Risk Factors Associated with Optic Nerve Thinning in Sickle Cell Disease.

2025-11-06

Abstract excerpt

<title>Abstract</title> <p>Objectives To determine whether adults with sickle cell disease (SCD) without glaucoma exhibit subclinical optic neuropathy (ON) on optical coherence tomography (OCT) and to identify genetic, clinical, and biologic correlates of optic nerve thinning. Methods Monocentric, retrospective cross-sectional study of 185 eyes from 96 adults with SCD (116 eyes/59 HbSS; 69 eyes/37 HbSC) and 40 ey...

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Literature Corpus work
ce2b5354-a308-53a5-9f78-99a54c8156cf
DOI
10.21203/rs.3.rs-7667965/v1
Open publication

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