Back to search

Article

Long-term immune dysfunction induced by sepsis is dependent on age

2022-12-30

Abstract excerpt

<h4>Background: </h4> and Purpose: Sepsis-surviving adult individuals commonly develop immunosuppression and increased susceptibility to secondary infections, outcome mediated by the axis IL-33/ILC2s/M2 macrophages/Tregs. Nonetheless, the long-term immune consequences of pediatric sepsis are indeterminate. We sought to investigate the role of age in the genesis of immunosuppression following sepsis. Experimental A...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
cdc8e355-2c64-5c21-a1f2-9c7d46248013
DOI
10.22541/au.167241098.81593871/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Long-term immune dysfunction induced by sepsis is dependent on ageDOI 10.22541/au.167241098.81593871/v1
Epigenetic Biomarkers for Human Sepsis and Septic Shock: Insights from ImmunosuppressionSemantic proximity
Pediatric Sepsis: Evolving Subphenotypes, Overlap Syndromes, and the Path to Precision Therapies.Semantic proximity
Epigenetic regulation of immune cell functions during post-septic immunosuppressionSemantic proximity
IL-33 controls IL-22-dependent antibacterial defense by modulating the microbiotaSemantic proximity
Age- and Sex- Driven Transcriptional and Metabolic Diversity in Myeloid-Derived Suppressor Cells After Mouse SepsisSemantic proximity
The Evolutionary Role of the IL-33/ST2 System in Host Immune DefenceSemantic proximity
Paternal sepsis induces alterations of the sperm methylome and dampens offspring immune responses—an animal studySemantic proximity
Biological Aging, Immune Phenotypes, and Susceptibility to COVID-19 and Sepsis: A Mendelian Randomization Study.Semantic proximity
Sepsis leads to lasting changes in phenotype and function of naïve CD8 T cells.Semantic proximity
Interleukin-27-dependent transcriptome signatures during neonatal sepsisSemantic proximity
IL-33 controls IL-22-dependent antibacterial defense by modulating the microbiota.Semantic proximity
DNA Methylation Analysis to Unravel Altered Genetic Pathways Underlying Early Onset and Late Onset Neonatal Sepsis. A Pilot StudySemantic proximity
Select a neighboring publication to make it the new centre.